Guide Pharmacometrics: The Science of Quantitative Pharmacology

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Technology, Pharmaceutical--methods. More Details added author. Ette, Ene I. Williams, Paul J. A Look Inside Reviews. To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities. Back Cover Copy. Learn how to perform pharmacometrics to improve drug development success rates This landmark text is the first to pull together and present in one volume the many facets of pharmacometrics. It features an international team of editors and authors who are experts in the field.

Readers gain the knowledge base needed to perform pharmacometric analyses, interpret the results, and communicate these results to key decision makers. In particular, the text emphasizes the role of pharmacometrics in drug development, reflecting the field's enormous potential to increase drug development productivity. Following an introduction that sets forth key landmarks in the history of pharmacometrics, a section on general principles features such topics as essential programming methods and techniques for pharmacometric analysis software validation. Readers can reproduce the examples themselves and gain a deeper understanding of the many practical benefits of pharmacometrics.

More experienced pharmacometricians will want to keep the text on hand to address questions and further develop their skills.


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Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. This text lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a set of tools for the training and development of pharmacometricians. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them.

Pharmacometrics: The Science of Quantitative Pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for the training and development of pharmacometricians. Edited and written by key leaders in the field, this flagship text on pharmacometrics: Integrates theory and practice to let the reader apply principles and concepts. Provides a comprehensive set of tools for training and developing expertise in the pharmacometric field.


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Is unique in including computer code information with the examples. This volume is an invaluable resource for all pharmacometricians, statisticians, teachers, graduate and undergraduate students in academia, industry, and regulatory agencies. Table of Contents provided by Publisher. All Rights Reserved. This information is provided by a service that aggregates data from review sources and other sources that are often consulted by libraries, and readers.

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Pharmacometrics: The Science of Quantitative Pharmacology. Ene I. Ette and Paul J. Williams

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Pharmacodynamic and Pharmacokinetic Modeling of Data - Module 5, Session 2

Pharmacometrics: The Science of Quantitative Pharmacology. Selected type: Hardcover. Added to Your Shopping Cart. Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them.

Pharmacometrics: The Science of Quantitative Pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for the training and development of pharmacometricians. Edited and written by key leaders in the field, this flagship text on pharmacometrics: Integrates theory and practice to let the reader apply principles and concepts.

Model-Based Drug Development: The Road to Quantitative Pharmacology

Provides a comprehensive set of tools for training and developing expertise in the pharmacometric field. Is unique in including computer code information with the examples.


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He is also an adjunct professor of applied pharmaceutical sciences at the University of Rhode Island. Ette was a pioneer pharmacometric staff in the Office of Clinical Pharmacology and Biopharmaceutics at the Food and Drug Administration, where he developed the popular reference Guidance for Industry: Population Pharmacokinetics. From —, he was an FDA Consultant. In recognition of his contributions to clinical pharmacy and clinical pharmacology, Dr. Ette is chairman of the pharmacometrics panel of The Annals of Pharmacotherapy editorial board.

Permissions Request permission to reuse content from this site. Table of contents Dedication. Chapter 1. Pharmacometrics: Impacting Drug Development and Pharmacotherpay. Chapter 2. General Principles of Programming Computer and Statistical. Chapter 3. Validation of Software for Pharmacometric Analyses. Chapter 4. Chapter 5. Chapter 6.

Model-Based Drug Development: The Road to Quantitative Pharmacology | SpringerLink

Estimating the Dynamics of Drug Regimen Compliance. Chapter 7. Graphical Display for Modeling Population Data. Chapter 8.