Manual Isoenzymes (Outline Studies in Biology)

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Popular Features. New Releases. Description Isoenzymes were 'discovered' 20 years ago and were at first regarded as interesting but rare occurrences. Since then a wealth of information on enzyme heterogeneity has accrued and it now seems likely that at least half of all enzymes exist as isoenzymes. This is important in many areas of biological and medical science.

Isoenzymes in genetics and evolution

Thus isoenzyme studies have provided the main experimental substance for the neutral drift controversy in genetics and evolution; they have greatly extended our understanding of metabolic regulation not only in animals but also in bacteria and plants; their existence has made available a multitude of highly sensitive markers for the study of differentiation and development, as well as providing indices of aberrant gene expression in carcinogenesis and other pathological processes. Iso- enzymes are also being used increasingly in diagnostic clinical bio- chemistry.

It is surprising that this phenomenon which affects such a high pro- portion of enzymes and is clearly important in biochemistry should receive such scant attention in the standard textbooks of that subject, the formal treatment of isoenzymology in these rarely exceeding one or two pages. This may be because the 'pure biochemist' has tended to regard variation in enzyme properties between tissues more as an unwanted complication than as a potential source of insight into diversity of biological function.

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Muscle Contraction Clive R. Biochemical Genetics R. A Biochemical Approach to Nutrition R. Thus isoenzyme studies have provided the main experimental substance for the neutral drift controversy in genetics and evolution; they have greatly extended our understanding of metabolic regulation not only in animals but also in bacteria and plants; their existence has made available a multitude of highly sensitive markers for the study of differentiation and development, as well as providing indices of aberrant gene expression in carcinogenesis and other pathological processes.

This may be because the 'pure biochemist' has tended to regard variation in enzyme properties between tissues more as an unwanted complication than as a potential source of insight into diversity of biological function. JavaScript is currently disabled, this site works much better if you enable JavaScript in your browser.

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  • References.
  • The use of isozyme characters in systematic studies!
  • Table of Contents.
  • Enzyme regulation.
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FAQ Policy. About this book Isoenzymes were 'discovered' 20 years ago and were at first regarded as interesting but rare occurrences. Show all. Table of contents 8 chapters Table of contents 8 chapters Introduction Rider, C.

Pages Structural aspects of isoenzymes Rider, C. Isoenzymes in genetics and evolution Rider, C.